And on this day in 2003, the Human Genome Projectannounced that it had finished identifying and mapping the genes in human DNA. The project began in 1989; it's the largest single investigation in modern science, and it was completed ahead of schedule and under budget. A parallel project in the private sector, run by Craig Venter and his company Celera Genomics, was undertaken in 1998. The company intended to patent 100 to 300 genes, but President Clinton declared in 2000 that the genome sequences could not be patented, and that the research should be given freely to the scientific community. Celera's stock plummeted and the biotechnology sector was sent reeling.
The project yielded some surprising findings. Scientists expected to find that humans had more than 100,000 genes; it turns out we have only around 30,000 — about the same as mice. The genes themselves are mostly similar to mice and other mammals too, with only a few exceptions. The gene sequence is published on the Internet and available to the public. The next phase of the research, the International HapMap Project, aims to establish a list of common genetic variants, since everyone's DNA — with the exception of identical twins and clones — is unique to them.
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